Why the study?
Evidence was lacking on the comparative effectiveness of pharmacist-led anticoagulant interventions versus usual care regarding therapy appropriateness and clinical outcomes.
Do pharmacist-led interventions improve the appropriateness and clinical outcomes of anticoagulant therapy compared to usual care in patients receiving anticoagulants?
Population
10 374 intervention and 11 840 control patients across 35 studies
Comparison
Pharmacist-led interventions vs usual care
Design
Systematic review and meta-analysis of randomized controlled trials, quasi-experimental, and cohort studies
Authors
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Supports pharmacist integration into anticoagulation care; extends evidence for multidisciplinary models improving safety.
Do pharmacist-led interventions improve the appropriateness and clinical outcomes of anticoagulant therapy compared to usual care in patients receiving anticoagulants?
Pharmacist-led interventions significantly improve the appropriateness of anticoagulant therapy and reduce bleeding and hospitalizations compared to usual care.
Kefale et al. (2024) studied this question.