Contrast-enhanced cine MR imaging strongly agreed with standard MR imaging for evaluating microvascular obstruction (IC 0.88-0.96, P<0.001), while reducing imaging time by 34%.
Observational (n=80)
No
Does contrast material-enhanced cine MR imaging accurately evaluate microvascular obstruction and myocardial function compared to standard MR imaging in patients with acute myocardial infarction after reperfusion therapy?
Contrast-enhanced cine MR imaging is a reliable and time-saving alternative to standard MR imaging for assessing microvascular obstruction and myocardial function after acute myocardial infarction.
Effect estimate: IC 0.96
p-value: p=< .001
UNLABELLED: This study was approved by the Human Investigation Committee of William Beaumont Hospital, and all patients gave informed consent. The purpose of this study was to prospectively compare contrast material-enhanced cine magnetic resonance (MR) imaging with more-standard MR imaging for the evaluation of microvascular obstruction and myocardial function in 80 patients (56 men, 24 women; mean age, 57 years; range, 29-80 years) with acute myocardial infarction after reperfusion therapy. Findings at contrast-enhanced cine MR imaging agreed with the global and transmural extent of microvascular obstruction at first-pass perfusion (intraclass correlation coefficient IC of 0.96 P < .001 and 0.88 P < .001, respectively) and inversion-recovery gradient-echo (IC of 0.90 P < .001 and 0.93 P < .001, respectively) MR imaging. There was no significant difference between myocardial function parameters before and after contrast material enhancement. Contrast-enhanced cine MR imaging reduced imaging time by 34% (11 of 32 minutes) and improved spatial resolution. SUPPLEMENTAL MATERIAL: radiology.rsnajnls.org/cgi/content/full/240/2/529/DC1
Raff et al. (Tue,) conducted a observational in Acute myocardial infarction after reperfusion therapy (n=80). Contrast material-enhanced cine MR imaging vs. Standard MR imaging (first-pass perfusion and inversion-recovery gradient-echo) was evaluated on Global and transmural extent of microvascular obstruction (IC 0.96, p=< .001). Contrast-enhanced cine MR imaging strongly agreed with standard MR imaging for evaluating microvascular obstruction (IC 0.88-0.96, P<0.001), while reducing imaging time by 34%.
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