Lower preoperative Geriatric Nutritional Risk Index scores were independently associated with postoperative acute kidney injury in patients undergoing noncardiac surgery.
Cohort
Does preoperative GNRI predict postoperative AKI in patients undergoing noncardiac surgery?
Preoperative malnutrition, as indicated by a lower Geriatric Nutritional Risk Index, is an independent predictor of postoperative acute kidney injury following noncardiac surgery.
Rationale & Objective: Malnutrition could be a risk factor for postoperative acute kidney injury (AKI). The geriatric nutritional risk index (GNRI) is a simple indicator of malnutrition, and this study examined the association of preoperative GNRI with postoperative AKI in noncardiac surgery. Study Design: A retrospective cohort study. Setting & Population: , and preoperative dialysis were excluded. Predictor: Preoperative GNRI. Outcome: AKI within 7 days after surgery. Analytical Approach: Multivariable logistic regression and restricted cubic spline analysis were performed to examine the association of preoperative GNRI with AKI. Results: for interaction = 0.78, 0.55, and 0.84, respectively). In sensitivity analyses, the association of GNRI with AKI was consistent using multiple imputations on missing data. Multinomial logistic regression indicated severe malnutrition tended to be associated with more severe AKI. Limitations: The presence of residual unknown confounders is a concern although a maximal effort was made to adjust for possible confounders. Conclusions: Lower GNRIs were independently associated with postoperative AKI irrespective of patients' age, malignancy, or inflammation. Improvement of preoperative malnutrition may reduce postoperative AKI.
Nishimoto et al. (Mon,) conducted a cohort in Noncardiac surgery. Preoperative Geriatric Nutritional Risk Index (GNRI) was evaluated on Acute kidney injury (AKI) within 7 days after surgery. Lower preoperative Geriatric Nutritional Risk Index scores were independently associated with postoperative acute kidney injury in patients undergoing noncardiac surgery.