Key result
Long sleep links to ~155% higher odds of severe abdominal aortic calcification in men with CKD.
Why the study?
No studies had explored the correlation between sleep duration and abdominal aortic calcification, particularly in patients with chronic kidney disease who face higher rates of both.
Is sleep duration associated with abdominal aortic calcification in adults with chronic kidney disease?
Cross-Sectional (n=2,996)
Yes
Is sleep duration associated with abdominal aortic calcification in adults with chronic kidney disease?
Effect estimate: OR 2.55 (95% CI 1.02, 6.36)
p-value: p=0.044
Long sleep duration (≥ 9 hours) is associated with increased severity and risk of abdominal aortic calcification in male adults with chronic kidney disease.
There are no studies exploring the correlation between sleep duration and abdominal aortic calcification (AAC). This study aims to investigate this relationship and its significance. Additionally, given the higher prevalence of sleep disorders and AAC in patients with chronic kidney disease (CKD), we conducted further studies in this population. We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014. Sleep duration was assessed by a sleep questionnaire and categorized into 2-5, 6-8, and ≥ 9 h. The AAC-24 score is determined using the Kauppila scoring system and used for AAC assessment. Multivariable linear and logistic regression analysis were used to explore the relationship between sleep duration and AAC. Among the 2,996 participants, 14.29% reported nightly short sleep (2-5 h), 77.64% reported intermediate sleep (6-8 h), and 8.08% reported long sleep (≥ 9 h). After adjusting for potential confounding factors, among male participants with CKD, long sleep (≥ 9 h) significantly increased AAC-24 scores compared with intermediate sleep (6-8 h) (β: 2.12; 95% CI: 0.75, 3.50), and the risk of severe AAC (SAAC) was increased by 1.55 times (OR: 2.55; 95% CI: 1.02, 6.36). And among female CKD and non-CKD participants, sleep duration was not associated with AAC. Long sleep duration increases the risk of AAC among male adults with CKD. Prospective studies are needed to confirm this finding.
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Wang et al. (2024) conducted a cross-sectional in Chronic kidney disease (n=2,996). Long sleep duration (≥ 9 hours) vs. Intermediate sleep duration (6-8 hours) was evaluated on Severe abdominal aortic calcification (SAAC) in male participants with CKD (OR 2.55, 95% CI 1.02, 6.36, p=0.044). Long sleep duration (≥ 9 hours) significantly increased the risk of severe abdominal aortic calcification by 1.55 times (OR 2.55) compared to intermediate sleep among male adults with chronic kidney disease.
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