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There is emerging evidence of antibiotic resistance, particularly for antibiotics commonly used to treat secondary bacterial infections in COVID-19 patients. The overuse of antibiotics in COVID-19 patients has contributed to the development of antibiotic-resistant bacterial strains against amoxicillin, azithromycin, cephalosporins, ciprofloxacin, and carbapenem. The most resistant bacteria isolated from COVID-19 patients include Klebsiella pneumonia, Acinetobacter baumannii, and Pseudomonas aeruginosa, which showed multiple antibiotic resistance. The increasing rates of antibiotic resistance are labeled as a “silent pandemic” as post covid-19 bacterial infections caused by deadly pathogens are the most significant threats to global health.
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