12-lead ECG recordings in a patient with Brugada syndrome demonstrated progressive RS-T segment and J wave elevation immediately preceding and following an episode of ventricular fibrillation.
Case Report (n=1)
Dynamic ECG changes in a Brugada syndrome patient support the hypothesis that RS-T elevation and subsequent VF are related to a transient outward current-mediated spike-and-dome morphology.
We present a patient with Brugada syndrome in whom 12-lead ECGs were recorded just before and after an episode of ventricular fibrillation (VF). A progressive elevation of both the RS-T segment and J waves just preceding and following the VF, and a close relationship between the amplitude of the RS-T segment and the preceding R-R intervals during atrial fibrillation, were documented. These findings support the hypothesis that RS-T elevation and a subsequent VF are related to a transient outward current-mediated spike-and-dome morphology of the epicardial action potential.
Matsuo et al. (1998) conducted a case report in Brugada syndrome (n=1). 12-lead ECG was evaluated on Dynamic changes of RS-T segment and J waves. 12-lead ECG recordings in a patient with Brugada syndrome demonstrated progressive RS-T segment and J wave elevation immediately preceding and following an episode of ventricular fibrillation.