Key result
The Surgical Apgar Score remained strongly correlated with major postoperative complications after risk-adjustment, with scores of 9-10 reducing the odds by half (LR 0.52; 95% CI 0.35-0.78).
Why the study?
Does the Surgical Apgar Score predict major postoperative complications independently of preoperative risk in general and vascular surgery patients?
Cohort (n=4,119)
No
Does the Surgical Apgar Score predict major postoperative complications independently of preoperative risk in general and vascular surgery patients?
Effect estimate: LR 0.52 (95% CI 0.35-0.78)
p-value: p=<0.0001
The Surgical Apgar Score independently predicts 30-day major postoperative complications beyond fixed preoperative risk, reflecting the impact of intraoperative management.
May aid postoperative risk stratification beyond preoperative factors; extends observational validation but remains hypothesis-generating pending prospective trials.
OBJECTIVE: To evaluate whether Surgical Apgar Scores measure the relationship between intraoperative care and surgical outcomes. SUMMARY BACKGROUND DATA: With preoperative risk-adjustment now well-developed, the role of intraoperative performance in surgical outcomes may be considered. We previously derived and validated a 10-point Surgical Apgar Score--based on intraoperative blood loss, heart rate, and blood pressure--that effectively predicts major postoperative complications within 30 days of general and vascular surgery. This study evaluates whether the predictive value of this score comes solely from patients' preoperative risk or also measures care in the operating room. METHODS: Among a systematic sample of 4119 general and vascular surgery patients at a major academic hospital, we constructed a detailed risk-prediction model including 27 patient-comorbidity and procedure-complexity variables, and computed patients' propensity to suffer a major postoperative complication. We evaluated the prognostic value of patients' Surgical Apgar Scores before and after adjustment for this preoperative risk. RESULTS: After risk-adjustment, the Surgical Apgar Score remained strongly correlated with postoperative outcomes (P < 0.0001). Odds of major complications among average-scoring patients (scores 7-8) were equivalent to preoperative predictions (likelihood ratio (LR) 1.05, 95% CI 0.78-1.41), significantly decreased for those who achieved the best scores of 9-10 (LR 0.52, 95% CI 0.35-0.78), and were significantly poorer for those with low scores--LRs 1.60 (1.12-2.28) for scores 5-6, and 2.80 (1.50-5.21) for scores 0-4. CONCLUSIONS: Even after accounting for fixed preoperative risk--due to patients' acute condition, comorbidities and/or operative complexity--the Surgical Apgar Score appears to detect differences in intraoperative management that reduce odds of major complications by half or increase them by nearly 3-fold.
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Regenbogen et al. (2008) conducted a cohort in General and vascular surgery (n=4,119). Surgical Apgar Score vs. Average scores (7-8) or preoperative risk prediction was evaluated on Major postoperative complications within 30 days (LR 0.52, 95% CI 0.35-0.78, p=<0.0001). The Surgical Apgar Score remained strongly correlated with major postoperative complications after risk-adjustment, with scores of 9-10 reducing the odds by half (LR 0.52; 95% CI 0.35-0.78).
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