Key result
Dilated left atrium significantly increased the risk of atrial fibrillation recurrence after single circumferential pulmonary vein isolation (WMD 1.87 mm; 95% CI 1.26-2.48; P<0.001).
Why the study?
Does left atrial diameter predict atrial fibrillation recurrence after single circumferential pulmonary vein isolation?
Population
3,750 patients with atrial fibrillation undergoing single circumferential pulmonary vein isolation across 22…
Comparison
Larger left atrial diameter vs Smaller left atrial diameter
Design
Meta-analysis
Authors
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May guide pre-PVI risk stratification and counseling; confirms LA diameter as recurrence predictor but leaves practice change open.
Meta-Analysis (n=3,750)
Does left atrial diameter predict atrial fibrillation recurrence after single circumferential pulmonary vein isolation?
Effect estimate: WMD 1.87 mm (95% CI 1.26-2.48)
p-value: p=< 0.001
Dilated left atrium significantly increases the risk of atrial fibrillation recurrence after single circumferential pulmonary vein isolation, particularly in long-term follow-up.
Zhuang et al. (2011) conducted a meta-analysis in Atrial fibrillation (n=3,750). Left atrial enlargement vs. Normal left atrial size was evaluated on Difference in left atrial diameter between patients with and without atrial fibrillation recurrence (WMD 1.87 mm, 95% CI 1.26-2.48, p=< 0.001). Dilated left atrium significantly increased the risk of atrial fibrillation recurrence after single circumferential pulmonary vein isolation (WMD 1.87 mm; 95% CI 1.26-2.48; P<0.001).
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