What is the clinical evidence from this study?

Study design: Observational. Population: Atrial fibrillation secondary to cardiac lesions requiring surgery (n=101). Intervention: Modified maze procedure combined with simultaneous open heart surgery. Primary outcome: Postoperative sinus rhythm.

What question did this study set out to answer?

To evaluate the safety and effectiveness of a modified maze procedure for treating atrial fibrillation during simultaneous cardiac surgery.

November 1, 1995Circulation

Modified Maze Procedure for Patients With Atrial Fibrillation Undergoing Simultaneous Open Heart Surgery

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Key result

A modified maze procedure combined with simultaneous open heart surgery restored sinus rhythm in 82% of patients with atrial fibrillation at 1.0 to 3.1 years follow-up.

Why the study?

Does a modified maze procedure combined with open heart surgery improve sinus rhythm recovery in patients with atrial fibrillation?

Population

101 patients with atrial fibrillation secondary to cardiac lesions requiring surgery

Design

Case_series

Follow-up

1.0 to 3.1 years

Authors

YKY KosakaiAstellas Pharma (Japan)AKAkira T. KawaguchiTokai University FIF IsobeOkayama University

Discussion

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Implication

Supports feasibility of combined maze during open-heart surgery; leaves open efficacy confirmation in randomized trials.

Key Points

To evaluate the safety and effectiveness of a modified maze procedure for treating atrial fibrillation during simultaneous cardiac surgery.
Combined modified maze procedure with open heart surgery in 101 patients.
Measured postoperative atrial rhythm, incidence of thromboembolic events, and patient demographics.
Follow-up duration ranged from 1.0 to 3.1 years, totaling 190 patient-years.
Postoperative sinus rhythm achieved in 83% of patients, with 14% persisting in atrial fibrillation.
83% of patients off anticoagulation therapy and reported recovery of atrial rhythm and contraction.
Only 2% early mortality with no late deaths observed.

Study Design

Type

Observational (n=101)

Structured PICO

Does a modified maze procedure combined with open heart surgery improve sinus rhythm recovery in patients with atrial fibrillation?

Population

101 patients with atrial fibrillation secondary to cardiac lesions requiring surgery (87 valvular procedures, 12 repair of congenital anomalies, 2 other procedures, including 24 repeat operations)

Intervention

Modified maze procedure combined with simultaneous open heart surgery

Outcome

Postoperative rhythm (sinus rhythm recovery)surrogate

A modified maze procedure combined with open heart surgery is safe and highly effective for restoring sinus rhythm and atrial contraction in patients with atrial fibrillation.

Cite This Study

Kosakai et al. (1995) conducted an observational in Atrial fibrillation secondary to cardiac lesions requiring surgery (n=101). Modified maze procedure combined with simultaneous open heart surgery was evaluated on Postoperative sinus rhythm. A modified maze procedure combined with simultaneous open heart surgery restored sinus rhythm in 82% of patients with atrial fibrillation at 1.0 to 3.1 years follow-up.

synapsesocial.com/papers/6a0ea97353f874f2b2229cf7 https://doi.org/10.1161/01.cir.92.9.359

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF AF ablation outcomes

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Modified Maze Procedure for Patients With Atrial Fibrillation Undergoing Simultaneous Open Heart Surgery

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Modified Maze Procedure for Patients With Atrial Fibrillation Undergoing Simultaneous Open Heart Surgery

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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