Hybrid Pharmacologic and Ablative Therapy: A Novel and Effective Approach for the Management of Atrial Fibrillation
Key result
Combined ablation and antiarrhythmic drug therapy maintained sinus rhythm in 88.9% of patients who converted from atrial fibrillation to typical atrial flutter.
Why the study?
Does combined ablation and antiarrhythmic drug therapy improve maintenance of sinus rhythm in patients with atrial fibrillation who converted to atrial flutter on antiarrhythmic drugs?
Study Design
Type
Observational (n=13)
Structured PICO
Does combined ablation and antiarrhythmic drug therapy improve maintenance of sinus rhythm in patients with atrial fibrillation who converted to atrial flutter on antiarrhythmic drugs?
P
Population
13 patients (mean age 61.5 +/- 16.2 years) with atrial fibrillation who converted to electrocardiographic atrial flutter during antiarrhythmic drug treatment.
I
Intervention
Combined pharmacologic and simple ablative therapies (ablation and continuation of antiarrhythmic drug therapy).
O
Outcome
Recurrences of atrial arrhythmias (maintenance of sinus rhythm)
Combined ablation and antiarrhythmic therapy is an effective strategy for maintaining sinus rhythm in patients whose atrial fibrillation converts to atrial flutter on medication.
Authors
Discussion
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Implication
May support combined ablation plus antiarrhythmic drugs after AF-to-AFL conversion; leaves open need for randomized confirmation.
Cite This Study
Huang et al. (1998) conducted an observational in Atrial fibrillation (n=13). Ablation and continuation of antiarrhythmic drugs was evaluated on Maintenance of sinus rhythm. Combined ablation and antiarrhythmic drug therapy maintained sinus rhythm in 88.9% of patients who converted from atrial fibrillation to typical atrial flutter.