Key result
Symmetric tethering in chronic ischemic mitral regurgitation was associated with significantly higher indexes of global left ventricular remodeling compared to asymmetric tethering (all p < 0.0001).
Why the study?
Do different tethering patterns (symmetric vs asymmetric) in chronic ischemic mitral regurgitation correlate with distinct degrees of LV remodeling and regurgitant jet characteristics?
Population
92 consecutive patients with chronic ischemic mitral regurgitation (MR) due to restricted motion
Comparison
Echocardiographic classification into symmetric… vs Asymmetric tethering pattern
Design
Cross-sectional
Authors
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Tethering pattern assessment may refine ischemic MR evaluation; leaves open prognostic value and therapeutic implications.
Observational (n=92)
Do different tethering patterns (symmetric vs asymmetric) in chronic ischemic mitral regurgitation correlate with distinct degrees of LV remodeling and regurgitant jet characteristics?
p-value: p=<0.0001
Patients with chronic ischemic mitral regurgitation can be classified by tethering pattern, with symmetric tethering associated with significantly worse global and local LV remodeling compared to asymmetric tethering.
Eustachio Agricola (2004) conducted an observational in Chronic ischemic mitral regurgitation (n=92). Symmetric tethering pattern vs. Asymmetric tethering pattern was evaluated on Mitral deformation indexes, LV global (volume, function and sphericity) and local remodeling (p=<0.0001). Symmetric tethering in chronic ischemic mitral regurgitation was associated with significantly higher indexes of global left ventricular remodeling compared to asymmetric tethering (all p < 0.0001).
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