Cardiac fibrillation arises through a quasiperiodic stage of period and amplitude modulation, demonstrating that it is a form of spatio-temporal chaos rather than a purely random process.
p-value: p=<0.01
In cardiac fibrillation, disorganized waves of electrical activity meander through the heart, and coherent contractile function is lost. We studied fibrillation in three stationary forms: in human chronic atrial fibrillation, in a stabilized form of canine ventricular fibrillation, and in fibrillation-like activity in thin sheets of canine and human ventricular tissue in vitro. We also created a computer model of fibrillation. In all four studies, evidence indicated that fibrillation arose through a quasiperiodic stage of period and amplitude modulation, thus exemplifying the "quasiperiodic transition to chaos" first suggested by Ruelle and Takens. This suggests that fibrillation is a form of spatio-temporal chaos, a finding that implies new therapeutic approaches.
Garfinkel et al. (Wed,) conducted a other in Cardiac fibrillation (Atrial and Ventricular). Cardiac fibrillation arises through a quasiperiodic stage of period and amplitude modulation, demonstrating that it is a form of spatio-temporal chaos rather than a purely random process.
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