Key result
Left atrial volume linked to ~185% greater atrial fibrillation risk in hypertrophic cardiomyopathy.
Why the study?
The study sought to investigate the association between CMR imaging parameters and AF in patients with hypertrophic cardiomyopathy.
Do cardiac magnetic resonance imaging parameters predict atrial fibrillation in patients with hypertrophic cardiomyopathy?
Observational (n=122)
No
Do cardiac magnetic resonance imaging parameters predict atrial fibrillation in patients with hypertrophic cardiomyopathy?
Effect estimate: OR 2.85 (95% CI 1.011-4.55)
p-value: p=0.0001
Left atrial volume measured by cardiac magnetic resonance imaging is an independent predictor of atrial fibrillation in patients with hypertrophic cardiomyopathy.
Purpose: The present study sought to investigate the association between Cardiac magnetic resonance (CMR) imaging parameters including late gadolinium enhancement (LGE), total left ventricular mass (TLVM), mitral regurgitation, and left atrial (LA) volume, with atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM). patients. Materials and Methods: Consecutive 122 patients with the diagnosis of HCM and together with having 48-hour Holter monitoring were included in the present work. Two experienced observers evaluated all CMR images. The correlation between AF and CMR parameters including TLVM, LA volume, the presence and extent of LGE, mitral regurgitation, and the maximum left ventricular thickness were evaluated. Results: Between the LA volume and AF, a significant correlation was observed. Additionally, TLVM was also associated with AF. The logistic multivariate analysis assessing TLVM, LA volume, and the extent of LGE revealed that only the left atrial volume was the independent predictor. Significant correlations were observed between the existence and extent of LGE, TLVM, mitral regurgitation and LA volume. Conclusion: The presence of LGE was positively correlated with LA volume. LA volume appears to be the most important independent predictor of AF in HCM patients.
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Güler et al. (2022) conducted an observational in Hypertrophic cardiomyopathy (n=122). Left atrial volume (CMR) was evaluated on Atrial fibrillation (OR 2.85, 95% CI 1.011-4.55, p=0.0001). Left atrial volume was the only independent predictor of atrial fibrillation in patients with hypertrophic cardiomyopathy (OR 2.85).
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