Key result
Primary MVP in children is linked to increased QT dispersion and ~50% ventricular arrhythmia incidence.
Why the study?
Does primary mitral valve prolapse increase QT dispersion and ventricular arrhythmias in children compared to healthy controls?
Case-Control (n=74)
Does primary mitral valve prolapse increase QT dispersion and ventricular arrhythmias in children compared to healthy controls?
Absolute Event Rate: 56% vs 43%
p-value: p=0.001
Children with primary mitral valve prolapse have increased QT dispersion and a higher prevalence of ventricular arrhythmias, suggesting QT dispersion may help identify those at risk for arrhythmias.
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May support QT dispersion monitoring for arrhythmia risk in pediatric MVP; leaves open prospective outcome validation.
İmamoğlu et al. (2016) conducted a case-control in primary mitral valve prolapse (n=74). Primary mitral valve prolapse vs. Healthy children was evaluated on QT dispersion (p=0.001). Children with primary mitral valve prolapse had significantly increased QT dispersion (56 vs 43 ms, p=0.001) and higher rates of ventricular arrhythmias (50% vs 18.8%, p=0.006) than healthy controls.
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