Age-adjusted mortality for heart failure and colon cancer in adults ≥65 years declined until 2015 but increased to 4.4 per 100,000 by 2020 (APC 2.55; 95% CI 0.08-8.19), with disparities noted.
Observational
Yes
Despite an overall decline in mortality for older adults with heart failure and colon cancer from 1999 to 2015, mortality rates have modestly increased since 2015, with persistent demographic and regional disparities.
Background: Heart failure (HF) and colorectal cancer (CRC) are major public health concerns among the aging population in the United States. This study aimed to investigate temporal, regional, urbanization and racial trends in mortality among adults with HF and CRC aged ≥65 years. Methods: Mortality data were sourced from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database, utilizing ICD-10 codes to identify deaths related to colon cancer and heart failure from 1999 to 2020. Age-adjusted mortality rates (AAMRs) per 100,000 individuals were calculated, along with Annual Percentage Changes (APCs) and their respective 95 % confidence intervals (CIs). Results: The AAMRs remained relatively stable between 1999 (8.5) and 2004 (7.3) (APC: -2.61; 95 % CI: -3.86, 0.09). From 2004 to 2009, a significant decline to 5.0 was observed (APC: -7.08; 95 % CI: -9.28, -3.58). Subsequently, the rates stabilized by 2015 (3.8) (APC: -4.84; 95 % CI: -6.58 to 2.04) but demonstrated a modest increase to 4.4 by 2020 (APC: 2.55; 95 % CI: 0.08 to 8.19). Mortality rates were consistently higher among males (6.7 vs. 4.5 for females) and varied across racial/ethnic groups, with Non-Hispanic (NH) Whites (5.7) and NH Black/African Americans (5.4) exhibiting the highest rates, while Hispanics (2.8) and NH Asians/Pacific Islanders (2.3) had the lowest. Regional disparities showed that the Midwest had the highest AAMRs (6.5) followed by the Northeast (5.4), West (5.2), and South (4.8). Additionally, non-metropolitan areas exhibited significantly higher rates than metropolitan areas (7.1 vs. 5.0, respectively). The states in the 90th percentile for AAMRs were West Virginia, Mississippi, South Dakota, Nebraska, and North Dakota. Conclusion: Although there was an overall decline in mortality rates during the study period, disparities remained evident, with higher mortality observed among males, non-Hispanic Whites, residents of the Midwest, and individuals in non-metropolitan areas. This highlights the need for targeted public health intervention.
Rahman et al. (Wed,) conducted a observational in Heart failure and colorectal cancer. Age-adjusted mortality for heart failure and colon cancer in adults ≥65 years declined until 2015 but increased to 4.4 per 100,000 by 2020 (APC 2.55; 95% CI 0.08-8.19), with disparities noted.