Key result
Intensive statin therapy is reviewed for its early clinical benefit in reducing the high rate of recurrent events within the first 6 months after acute coronary syndromes.
Why the study?
Does early intensive statin therapy reduce recurrent early events in patients with acute coronary syndromes?
Does early intensive statin therapy reduce recurrent early events in patients with acute coronary syndromes?
This review highlights the evidence supporting the early initiation of statin therapy following acute coronary syndromes to mitigate the risk of early recurrent events.
May support early intensive statin use post-ACS; leaves open need for updated randomized confirmation.
The long-term efficacy of statins for the primary and secondary prevention of coronary heart disease is well established; however, until recently, there was little trial-based evidence to support the early clinical benefit of these agents after acute coronary syndromes (ACS). This is particularly important as ACS is characterised by a high rate of recurrent early events in the first 6 months and (traditionally) lipid-lowering therapy was perceived to reduce coronary heart disease risk by lowering the significant risk of elevated cholesterol over many years. This paper reviews the current state of evidence from the key statin trials in ACS and their implications for the future management of ACS.
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Ray et al. (2006) conducted a review in Acute coronary syndromes (ACS). Intensive statin therapy was evaluated. Intensive statin therapy is reviewed for its early clinical benefit in reducing the high rate of recurrent events within the first 6 months after acute coronary syndromes.
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