Key result
Elective delivery cuts maternal complications ~36% versus expectant management in hypertensive pregnancies >34 weeks.
Why the study?
Does elective delivery reduce maternal and neonatal complications in women with pre-eclampsia compared to expectant management?
Population
1,501 women with pre-eclampsia or gestational hypertension from 7 RCTs
Comparison
Elective delivery vs Expectant management
Design
Meta-analysis
Authors
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Supports elective delivery >34 weeks in pre-eclampsia to cut maternal complications; reinforces timed-delivery guidelines.
Meta-Analysis (n=1,501)
Yes
Does elective delivery reduce maternal and neonatal complications in women with pre-eclampsia compared to expectant management?
Effect estimate: RR 0.64 (95% CI 0.51-0.80)
Absolute Event Rate: 23.3% vs 36.4%
p-value: p=0.0001
Elective delivery reduces maternal complications in pre-eclampsia beyond 34 weeks gestation but may increase neonatal complications if performed before 34 weeks.
Wang et al. (2017) conducted a meta-analysis in Pre-eclampsia or gestational hypertension (n=1,501). Elective delivery vs. Expectant management was evaluated on Maternal complications in women with pre-eclampsia or gestational hypertension >34 weeks gestation (RR 0.64, 95% CI 0.51-0.80, p=0.0001). Elective delivery significantly lowered the incidence of maternal complications compared to expectant management in women with pre-eclampsia or gestational hypertension >34 weeks gestation (RR 0.64).
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