PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 13, 1980New England Journal of Medicine319 citations

Ventricular Resection Guided by Epicardial and Endocardial Mapping for Treatment of Recurrent Ventricular Tachycardia

View Full Paper
LHLeonard N. HorowitzElectrophysiologyAHAlden H. HarkenElectrophysiologyJKJohn A. KastorUniversity of Maryland, Baltimore

Key Result

Ventricular resection guided by epicardial and endocardial mapping abolished recurrent ventricular tachycardia in all 25 surviving patients during 4 to 28 months of follow-up.

Study Design

Type

Observational (n=30)

Structured PICO

Does ventricular resection guided by epicardial and endocardial mapping prevent recurrence in patients with medically refractory ventricular tachycardia?

P
Population
30 consecutive patients with recurrent, medically refractory ventricular tachycardia
I
Intervention
Ventricular resection guided by epicardial and endocardial mapping during induced ventricular tachycardia (with concomitant aneurysmectomy in 27 patients and coronary-bypass grafting in 21 patients)
O
Outcome
Recurrence of ventricular tachycardiahard clinical

Ventricular resection guided by epicardial and endocardial mapping is highly effective in abolishing recurrent, medically refractory ventricular tachycardia.

Abstract

Recurrent, medically refractory ventricular tachycardia is usually associated with ventricular aneurysms after myocardial infarction, but aneurysmectomy alone has not been consistently effective in abolishing this dangerous arrhythmia. Therefore, we have used endocardial and epicardial mapping during induced ventricular tachycardia in 30 consecutive patients to identify the probable site where arrhythmia originated in the endocardial tissue. Complete resection of the site was possible in 27 patients, and partial resection in three. In addition aneurysmectomy was performed in 27 patients, and coronary-bypass grafting in 21. There were two operative and three late nonarrhythmic deaths. None of the 25 surviving patients have had ventricular tachycardia during follow-up of four to 28 months; three patients, who had incomplete resections, have required antiarrhythmic drugs. We conclude that surgical therapy of recurrent ventricular tachycardia can be improved through identification of the endocardial origin of the arrhythmia followed by appropriately guided resection.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Horowitz et al. (1980) conducted an observational in Recurrent, medically refractory ventricular tachycardia (n=30). Ventricular resection guided by epicardial and endocardial mapping was evaluated on Recurrence of ventricular tachycardia. Ventricular resection guided by epicardial and endocardial mapping abolished recurrent ventricular tachycardia in all 25 surviving patients during 4 to 28 months of follow-up.

synapsesocial.com/papers/6a0ecb291c5e2d2319f9e132https://doi.org/10.1056/nejm198003133021101
Ask AI
Helpful
Bookmark
Share
View Full Paper