What question did this study set out to answer?

To analyze various statistical methods used to compare rates and proportions related to health conditions and exposures.

March 1, 1959Biometrics

An Examination of Some Methods of Comparing Several Rates or Proportions

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This examination reports methods for assessing disease rates related to various exposures, implying nuanced statistical approaches are crucial.

To analyze various statistical methods used to compare rates and proportions related to health conditions and exposures.
Examined historical data on disease rates and exposures from studies on smoking, poliomyelitis vaccine, and congenital malformations.
Compared incidence and mortality rates in smokers versus nonsmokers and vaccine efficacy.
Evaluated different statistical approaches including relative risk and absolute differences.
Estimated vaccine effectiveness at 71.9% based on incident cases per population.
Relative risk for lung cancer in smokers versus nonsmokers calculated as 23.7 based on prevalence rates.
Berkson's method yielded an additional mortality rate of 1.59 per 1000 smokers, suggesting a need for more nuanced comparisons.

Mindel C. Sheps (1959) studied this question.

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This examination reports methods for assessing disease rates related to various exposures, implying nuanced statistical approaches are crucial.