Why the study?
Oral anticoagulants are effective for thromboprophylaxis in AF, but they are best avoided in patients who are intolerant, non-adherent, or have an unacceptably high bleeding risk.
The paper reviews the rationale for percutaneous left atrial appendage occlusion as an alternative to oral anticoagulation for high-risk patients with atrial fibrillation in South Africa.
May support left atrial appendage occlusion for high-bleeding-risk AF in South Africa; leaves open need for local prospective trials.
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Dippenaar et al. (2021) conducted a review in Atrial fibrillation. Percutaneous left atrial appendage occlusion was evaluated.
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