What question did this study set out to answer?

To investigate the relationship between serum C-reactive protein, cardiovascular risk factors, and 10-year mortality in elderly cohorts.

C-Reactive Protein, Cardiovascular Risk Factors, and Mortality in a Prospective Study in the Elderly

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Prospective study examines C-reactive protein's role in predicting mortality in elderly cohorts, suggesting future implications.

To investigate the relationship between serum C-reactive protein, cardiovascular risk factors, and 10-year mortality in elderly cohorts.
Analyzed serum CRP levels in 455 elderly individuals from the Helsinki Ageing Study at baseline and in 1998.
Conducted clinical examinations and retrieved mortality data from national registers over 10 years.
Measured CRP levels and correlated them with cardiovascular risk factors and mortality outcomes.
61% of the cohort died during the follow-up; mean CRP in survivors was 3.16 mg/L and 5.22 mg/L in nonsurvivors (P=0.017).
Baseline CRP significantly predicted 10-year mortality: risk ratio of 1.20 (95% CI 1.08 to 1.32) for total mortality, and 1.22 (95% CI 1.10 to 1.35) for cardiovascular mortality.
Prediction strength was observed mainly in the 75-year-old cohort, diminishing in older cohorts.

Strandberg et al. (2000) studied this question.

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