Key result
Higher CCTA-derived LVMI linked to ~1% greater odds of CAD and PAD.
Why the study?
Left ventricular mass is a critical marker of cardiovascular risk, but its association with coronary artery disease or peripheral artery disease when measured by coronary computed tomography angiography needed evaluation.
Does left ventricular mass index measured by CCTA associate with the presence of coronary artery disease or peripheral artery disease in patients undergoing screening?
Population
1,307 consecutive patients undergoing CCTA for CAD screening at Fukuoka University Hospital
Comparison
CAD (+) vs CAD (-) and PAD (+) vs PAD (-)
Design
Registry-based cross-sectional study
Authors
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Should not yet change screening; leaves open incremental value of CCTA-derived LVMI beyond traditional risks.
Cross-Sectional (n=1,307)
No
Does left ventricular mass index measured by CCTA associate with the presence of coronary artery disease or peripheral artery disease in patients undergoing screening?
Effect estimate: OR 1.01 (95% CI 1.01 - 1.02)
p-value: p=< 0.01
Left ventricular mass index determined by CCTA is independently associated with the presence of both CAD and PAD, suggesting its potential utility as an imaging biomarker for atherosclerotic cardiovascular diseases.
Tachibana et al. (2023) conducted a cross-sectional in Suspected Coronary Artery Disease (n=1,307). Left ventricular mass index (LVMI) was evaluated on Presence of Coronary Artery Disease (CAD) (OR 1.01, 95% CI 1.01 - 1.02, p=< 0.01). Left ventricular mass index determined by coronary computed tomography angiography was independently associated with the presence of coronary artery disease (OR 1.01) and peripheral artery disease.
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