Key result
Mitral valve prolapse has a lower prevalence and complication rate than previously thought, with no conclusive association to neuropsychiatric symptoms.
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Mitral valve prolapse is less prevalent and complicated than previously thought, with management primarily focused on monitoring mitral regurgitation, antibiotic prophylaxis when indicated, and reassurance.
Although mitral valve prolapse is common in developed countries, its prevalence and its complications are much lower among the general population than was previously thought. No association has been conclusively documented for a myriad of neuropsychiatric symptoms previously speculated to be associated with mitral valve prolapse. Moreover, the prevalence of mitral valve prolapse does not appear to be affected by male or female sex. The most important management issues are mitral regurgitation and antibiotic prophylaxis for procedures that can cause bacteremia. For patients who are asymptomatic, reassurance becomes a critical component of treatment. If symptoms develop because of severe mitral regurgitation and decreased cardiac reserve, surgery may be required.
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Mulumudi et al. (2001) conducted a review in Mitral valve prolapse. Mitral valve prolapse has a lower prevalence and complication rate than previously thought, with no conclusive association to neuropsychiatric symptoms.
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