Key result
AV sequential pacing in DDD mode with an optimum AV delay significantly improved cardiac output by 11% and stroke volume by 9% compared to AAI pacing with intrinsic ventricular conduction.
Why the study?
Does AV sequential pacing in DDD mode with optimum AV delay improve stroke volume and cardiac output compared to AAI pacing with intrinsic ventricular conduction in patients with DDD pacemakers and prolonged native AV delays?
Population
9 patients with DDD pacemakers who had intact AV conduction, normal ventricular activation, and native AV…
Comparison
AV sequential pacing in DDD mode with an optimum… vs AAI pacing with intrinsic ventricular conduction…
Authors
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May support AV optimization in DDD pacemakers with prolonged conduction; leaves open outcome benefits in prospective trials.
Observational (n=9)
Does AV sequential pacing in DDD mode with optimum AV delay improve stroke volume and cardiac output compared to AAI pacing with intrinsic ventricular conduction in patients with DDD pacemakers and prolonged native AV delays?
Effect estimate: 11% improvement in CO, 9% improvement in SV
AV sequential pacing with an optimum AV delay provides better hemodynamic performance than atrial pacing with intrinsic ventricular conduction when native AV conduction is prolonged > 220 msec.
Jutzy et al. (1992) conducted an observational in Patients with DDD pacemakers and native AV delays ≥ 200 msec (n=9). AV sequential pacing in DDD mode with optimum AV delay vs. AAI pacing with intrinsic ventricular conduction (prolonged AV interval) was evaluated on Stroke volume (SV) and cardiac output (CO) (11% improvement in CO, 9% improvement in SV). AV sequential pacing in DDD mode with an optimum AV delay significantly improved cardiac output by 11% and stroke volume by 9% compared to AAI pacing with intrinsic ventricular conduction.
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