Key result
An endocardial septal approach to His-Purkinje ventricular pacing using a new custom electrode was feasible in beagles, yielding a narrow paced QRS morphology and acceptable pacing parameters.
Why the study?
Does a new endocardial electrode implant approach allow feasible septal His-Purkinje ventricular pacing in a canine model?
Population
5 6-month-old beagles
Design
Preclinical
Authors
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Animal feasibility supports translational human studies; leaves open clinical safety and efficacy of endocardial septal His-Purkinje pacing.
Does a new endocardial electrode implant approach allow feasible septal His-Purkinje ventricular pacing in a canine model?
A novel endocardial septal approach for His-Purkinje ventricular pacing is feasible in canines, producing narrow QRS complexes and favorable pacing parameters.
Karpawich et al. (1992) studied Ventricular pacing (n=5). Endocardial septal approach to His-Purkinje ventricular pacing with a custom helical screw electrode was evaluated on Feasibility and pacing parameters (sensed R wave, slew rate, pacing impedance, and threshold). An endocardial septal approach to His-Purkinje ventricular pacing using a new custom electrode was feasible in beagles, yielding a narrow paced QRS morphology and acceptable pacing parameters.
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