Key result
Beta-blockers are first-line for symptomatic PVCs without structural heart disease, with ablation for refractory cases.
Why the study?
The objective was to review the literature on the causes and treatment recommendations for premature ventricular contractions without structural heart disease, and to describe an illustrative clinical case.
Beta-blockers are the first-line treatment for symptomatic PVCs without structural heart disease, while catheter ablation is recommended for drug-refractory cases or when PVCs cause cardiomyopathy.
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Supports beta-blocker preference for symptomatic PVCs without SHD; leaves open need for RCTs comparing ablation strategies.
Izabelė Lanauskaitė (2025) conducted a review in Premature ventricular contractions (PVCs) without structural heart disease. Beta-blockers, non-dihydropyridine calcium channel blockers, and radiofrequency ablation was evaluated. Beta-blockers are the first-line pharmacotherapy for symptomatic premature ventricular contractions without structural heart disease, while radiofrequency ablation is recommended for refractory cases.
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