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August 1, 1956Circulation218 citations

Left Axis Deviation

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RGRobert P. Grant

Key Result

An electrocardiographic-pathologic correlation of 672 cases identified a previously unrecognized QRS-complex syndrome of infarction without conventional Q waves.

Study Design

Type

Observational (n=672)

Structured PICO

P
Population
672 cases with post-mortem examination and electrocardiograms taken during the last weeks of life
O
Outcome
Correlation of left axis deviation with left ventricular hypertrophy, myocardial infarction, and other factorssurrogate

This classic electrocardiographic-pathologic correlation study elucidates the anatomic and pathologic factors contributing to left axis deviation and describes a novel non-Q wave infarction pattern.

Abstract

Our understanding of the meaning of the electrocardiogram is greatly furthered by careful comparison of cardiac hypertrophy and cardiac damage observed post mortem with electrocardiograms taken during the last weeks of life. An electrocardiographic-pathologic correlation of 672 cases is reported in which the roles of left ventricular hypertrophy, myocardial infarction, and other factorsin the production of left axis deviation are examined. A heretofore unrecognized QRS-complex syndrome of infarction is described in which the QRS forces are diagnostically abnormal but no "Q waves" are seen in the conventional leads. The roles of hypertrophy, variations in body build, chronic pulmonary disease, and various types of "parietal block" in the production of left axis deviation are studied.

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Cite This Study

Robert P. Grant (1956) conducted an observational in Left axis deviation (n=672). An electrocardiographic-pathologic correlation of 672 cases identified a previously unrecognized QRS-complex syndrome of infarction without conventional Q waves.

synapsesocial.com/papers/6a0eed4c06ecbe833447f7behttps://doi.org/10.1161/01.cir.14.2.233
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