Key result
Different clinical states in psychiatric disorders are associated with distinctly different patterns of circadian heart rate, particularly during sleep, compared to healthy volunteers.
Why the study?
Does circadian heart rate architecture differ between patients with psychiatric disorders and healthy volunteers?
Observational
Does circadian heart rate architecture differ between patients with psychiatric disorders and healthy volunteers?
Circadian heart rate analysis may serve as a useful physiological adjunct in psychiatric assessment and treatment monitoring.
Psychiatric state links to distinct circadian HR patterns; hypothesis-generating for biomarker role but should not yet change practice.
Background: Data are presented to demonstrate dimensions of variation in circadian heart rate in patients under treatment for a psychiatric disorder and to comment on their clinical relevance. Method: Serial recordings of 24-hour heart rates were obtained from individuals under treatment for a psychiatric disorder and from healthy volunteers. Results: The mean 24-hour heart rate can vary independently of the circadian rate pattern or “rate architecture.” Sleep and waking heart rate can vary independently. Variations in circadian heart rate are state-dependent: broadly different clinical states are associated with distinctly different patterns of circadian heart rate, particularly during sleep. Conclusion: Different regulatory mechanisms or pathways are involved in mediating different aspects of circadian heart rate. An analysis of circadian heart rate can contribute useful physiological adjunct information to psychiatric assessment and the monitoring of patient response to treatment.
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Stampfer et al. (2013) conducted an observational in Psychiatric disorder. Serial recordings of 24-hour heart rates vs. Healthy volunteers was evaluated on Variations in circadian heart rate. Different clinical states in psychiatric disorders are associated with distinctly different patterns of circadian heart rate, particularly during sleep, compared to healthy volunteers.
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