Key result
XGBoost classifies hypertension in postmenopausal women with ~92% AUC, driven by age and waist circumference.
Why the study?
Hypertension prevalence increases sharply in postmenopausal women, highlighting the need for prevention strategies and identification of easily measurable risk factors using machine learning and explainable artificial intelligence.
Observational (n=3,289)
Yes
Effect estimate: AUC 92.12%
Machine learning analysis demonstrates that age and waist circumference are the most critical risk factors for hypertension in postmenopausal Korean women, emphasizing the need for strict waist circumference management.
Supports waist circumference monitoring in postmenopausal hypertension assessment; leaves open prospective validation of ML models.
In postmenopausal women, the prevalence of hypertension increases sharply, emphasizing the importance of its prevention. This increased risk highlights the critical need for effective prevention strategies specifically designed for this population. To address this issue, the present study aimed to identify easily measurable risk factors that contribute to hypertension in postmenopausal women using explainable artificial intelligence (XAI) and machine learning (ML) techniques. This study conducted hypertension classification by analyzing health checkup data from 3289 postmenopausal Korean women aged 55-79 years, extracted from the 2022-2023 Korea National Health Insurance Service (KNHIS) database, using XGBoost, SVM and ANN. XGBoost was the most effective model (AUC: 92.12%, MCC: 0.71) in hypertension classification. Shapley Additive exPlanations-based feature importance identified age and waist circumference (WC) as the most important risk factors for hypertension. In this study, blood pressure increased with variations in WC, a modifiable risk factor. These findings suggest that WC should be managed more strictly to prevent hypertension in postmenopausal women.
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Kim et al. (2025) conducted an observational in Hypertension (n=3,289). XGBoost and SHAP-based analysis vs. SVM and ANN was evaluated on Hypertension classification (AUC 92.12%). XGBoost effectively classified hypertension (AUC 92.12%) and identified age and waist circumference as the most important risk factors in postmenopausal Korean women.
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