Why the study?
Whether exercise prevents and treats DCM through gut microbiota regulation and the underlying mechanisms of this interaction remain largely unclear.
Does exercise prevent and treat diabetic cardiomyopathy through gut microbiota regulation?
Design
Review
Key result
Exercise may exert cardioprotective effects in diabetic cardiomyopathy by reshaping gut microbiota composition, enhancing intestinal barrier function, and modulating microbial metabolites.
Authors
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Hypothesis-generating for exercise via gut-heart axis in diabetic cardiomyopathy; prospective trials needed before clinical adoption.
Does exercise prevent and treat diabetic cardiomyopathy through gut microbiota regulation?
This review highlights the potential of exercise to modulate the gut-heart axis, offering a microbiota-based mechanism for its cardioprotective effects in diabetic cardiomyopathy.
Chen et al. (2026) conducted a review in Diabetic cardiomyopathy. Exercise was evaluated. Exercise may exert cardioprotective effects in diabetic cardiomyopathy by reshaping gut microbiota composition, enhancing intestinal barrier function, and modulating microbial metabolites.