Impact of body mass index on the outcome of catheter ablation of atrial fibrillation
Key result
Baseline obesity linked to ~22% higher risk of 12-month AF recurrence versus overweight patients.
- HR 1.223
- 95% CI 1.047 to 1.429
- P=0.011
- n=3,333
Why the study?
Does elevated baseline BMI increase the risk of AF recurrence at 12 months following catheter ablation in patients with atrial fibrillation?
Population
3,333 consecutive patients scheduled for atrial fibrillation ablation, with no specific exclusion criteria.
Comparison
Obesity or overweight vs Normal BMI (<25.0 kg/m2)
Design
Cohort
Follow-up
12 months
Authors
Discussion
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Implication
May support pre-ablation weight counseling in obese AF patients; leaves open whether weight loss reduces recurrence.
Study Design
Type
Observational (n=3,333)
Structured PICO
Does elevated baseline BMI increase the risk of AF recurrence at 12 months following catheter ablation in patients with atrial fibrillation?
P
Population
3,333 consecutive patients scheduled for atrial fibrillation (AF) ablation, with no specific exclusion criteria.
I
Intervention
Obesity (BMI ≥30.0 kg/m2) or overweight (BMI 25.5–29.0 kg/m2)
C
Comparator
Normal BMI (<25.0 kg/m2)
O
Outcome
AF recurrence at 12 months following catheter ablationhard clinical
Main Result
Effect estimate: HR 1.223 (95% CI 1.047 to 1.429)
p-value: p=0.011
Baseline obesity (BMI ≥30 kg/m2) is associated with a higher risk of AF recurrence at 12 months following catheter ablation compared to being overweight, highlighting the potential importance of preprocedural weight management.
Cite This Study
Glover et al. (2018) conducted an observational in Atrial fibrillation (n=3,333). Obesity (BMI ≥30.0 kg/m2) vs. Overweight (BMI 25.5–29.0 kg/m2) and normal BMI (<25.0 kg/m2) was evaluated on AF recurrence at 12 months (HR 1.223, 95% CI 1.047 to 1.429, p=0.011). Baseline obesity (BMI ≥30 kg/m2) was associated with a higher risk of recurrent atrial fibrillation at 12 months compared with overweight patients (HR 1.223; 95% CI 1.047 to 1.429; p=0.011).