Why the study?
Cerebral microbleeds are increasingly detected and considered a predictor of intracranial hemorrhage with oral anticoagulant use, warranting a summary of oral anticoagulant safety in relation to them.
What is the safety of oral anticoagulants in relation to cerebral microbleeds?
What is the safety of oral anticoagulants in relation to cerebral microbleeds?
This review summarizes data on the safety of oral anticoagulants specifically regarding the risk and predictive value of cerebral microbleeds for intracranial hemorrhage.
Cerebral microbleeds may predict ICH risk on OACs; leaves open whether screening alters management.
Oral anticoagulants are currently widely used, which requires continued research on their safety. With the improvement of diagnostic methods and power of magnetic resonance systems, cerebral microbleeds (CMBs), which are small deposits of hemosiderin-laden macrophages around the brain vessels, are increasingly being detected. Recently, CMB has been considered as a predictor of intracranial hemorrhage with oral anticoagulant use. In this regard, we decided to summarize the data on the safety of oral anticoagulants in relation to CMBs.
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Черняева et al. (2025) studied this question.
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