Key result
Deep classification model with prototype diversity penalty achieves 93.1% accuracy detecting ECG bradycardia vs baseline.
Why the study?
The emergence of deep learning networks created a need for explainable AI to give users and domain experts confidence in high-risk decisions.
Absolute Event Rate: 93.1% vs 92.1%
Leveraging learned prototypes in deep learning models can provide explainable insights for time-series classification tasks, such as detecting bradycardia in preterm infant ECGs.
Supports interpretable AI for neonatal ECG analysis; leaves open prospective validation before clinical adoption.
The emergence of deep learning networks raises a need for explainable AI so users and domain experts can be confident applying them to high-risk. In this paper, we leverage data from the latent space induced by learning models to learn stereotypical representations or "prototypes" training to elucidate the algorithmic decision-making process. We study leveraging prototypes effect classification decisions of two dimensional-series data in a few different settings: (1) electrocardiogram (ECG) to detect clinical bradycardia, a slowing of heart rate, in preterm, (2) respiration waveforms to detect apnea of prematurity, and (3) waveforms to classify spoken digits. We improve upon existing models by for increased prototype diversity and robustness, visualize how prototypes in the latent space are used by the model to distinguish, and show that prototypes are capable of learning features on two time-series data to produce explainable insights during tasks. We show that the prototypes are capable of learning-world features - bradycardia in ECG, apnea in respiration, and in speech - as well as features within sub-classes. Our novel work learned prototypical framework on two dimensional time-series data to explainable insights during classification tasks.
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Gee et al. (2019) studied Bradycardia and Apnea of prematurity (n=9,458). Deep classification model with prototype diversity penalty vs. Baseline model without prototype diversity penalty was evaluated on Classification accuracy for ECG bradycardia. A deep classification model with a prototype diversity penalty achieved a classification accuracy of 93.1% for detecting bradycardia in ECG waveforms, compared to 92.1% with the baseline model.
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