Predictors of Risk for Coronary Artery Lesions in Women With Symptoms of Coronary Artery Disease

BACKGROUND artery disease is a leading cause of mortality and morbidity in the world. Women differ from men with regard to artery disease in presentation, risk factors, prognosis and in acceptance of secondary prevention modalities. With to presentation, most of the women with coronary artery disease present at a later age. AND METHODS patients with STEMI, NSTEMI or chronic stable angina without significant comorbidities were studied and results were . 140 subjects were included in the study. The mean age of patients was 54.19±9.89 years, maximum number of patients were >60 yrs. of age. 21 (15%) were premenopausal and rest 119 (85%) were postmenopausal. 95 (68%) patients had angiographic of CAD while coronary angiography was normal in 45 (32%) patients. Total cholesterol, LDL, HDL were found to be from bivariable analysis, but in multivariable analysis, single independent predictor of a lesion in the coronary arteries found to be HDL cholesterol with adjusted risk ratio of 1.3 (1.1-1.5). with acute coronary syndromes present more with unstable angina/NSTEMI. Women are less likely to present with the associated with occlusive thrombus- that is, with infarction with ST elevation. Family history of premature coronary disease is an important risk factor in women. cholesterol, LDL, HDL were found to be significant from bivariable analysis, but in multivariable analysis, single predictor of a lesion in the coronary arteries was found to be HDL cholesterol.