Chemical self-replicating systems have been the subject of various investigations over the last 20 years. This mini review outlines the design of minimal model systems, mainly based on oligonucleotides and on peptides and artificial compounds, which implement template-directed reactions. In order to examine the reaction mechanism and to attain an exponential replication the development of self-replicating systems is pointed out.
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Patzke et al. (2007) studied this question.
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