Key result
There is currently no consensus on the appropriate perioperative management of anticoagulation for patients receiving long-term warfarin therapy who require elective surgery.
Why the study?
What is the appropriate perioperative management of anticoagulation for patients receiving long-term warfarin therapy undergoing elective surgery?
What is the appropriate perioperative management of anticoagulation for patients receiving long-term warfarin therapy undergoing elective surgery?
This review discusses the perioperative management of anticoagulation for patients on long-term warfarin therapy undergoing elective surgery, an area where clinical consensus has historically been lacking.
No consensus on perioperative warfarin management cautions against uniform protocols; leaves open evidence-based strategies for elective surgery patients.
The most common indications for warfarin therapy are atrial fibrillation, the presence of a mechanical heart valve, and venous thromboembolism.1,2 Treatment with warfarin presents a problem if patients with these indications need surgery, because the interruption of anticoagulant therapy increases the risk of thromboembolism. After warfarin therapy is discontinued, it takes several days for its antithrombotic effect to recede, and when it is resumed, several days are needed to reestablish therapeutic anticoagulation.There is no consensus on the appropriate perioperative management of anticoagulation for patients who have been receiving long-term warfarin therapy. Rational decisions about the treatment of such . . .
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Kearon et al. (1997) conducted a review in Patients receiving long-term warfarin therapy needing elective surgery. Perioperative management of anticoagulation was evaluated. There is currently no consensus on the appropriate perioperative management of anticoagulation for patients receiving long-term warfarin therapy who require elective surgery.
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