Key result
The strain from unwrapped phase (SUP) technique reconstructed full 3D strain maps from tagged MR images, demonstrating over 83% correlation with HARP techniques.
Why the study?
Does the strain from unwrapped phase (SUP) technique accurately measure 3D left ventricular strain compared to feature-based and HARP techniques in human subjects?
Does the strain from unwrapped phase (SUP) technique accurately measure 3D left ventricular strain compared to feature-based and HARP techniques in human subjects?
Effect estimate: Correlation >83%
The SUP technique can reconstruct full 3D strain maps from tagged MR images through the cardiac cycle with reasonable time and user interaction.
SUP supports feasible 3D LV strain mapping from tagged MRI; leaves open outcome validation before clinical adoption.
PURPOSE: To validate a method for measuring 3D left ventricular (LV) strain from phase-unwrapped harmonic phase (HARP) images derived from tagged cardiac magnetic resonance imaging (MRI). MATERIALS AND METHODS: A set of 40 human subjects were imaged with tagged MRI. In each study the HARP phase was computed and unwrapped in each short-axis and long-axis image. Inconsistencies in unwrapped phase were resolved using branch cuts manually placed with a graphical user interface. 3D strain maps were computed for all imaged timeframes in each study. The strain from unwrapped phase (SUP) and displacements were compared to those estimated by a feature-based (FB) technique and a HARP technique. RESULTS: 3D strain was computed in each timeframe through systole and mid-diastole in approximately 30 minutes per study. The standard deviation of the difference between strains measured by the FB and the SUP methods was less than 5% of the average of the strains from the two methods. The correlation between peak circumferential strain measured using the SUP and HARP techniques was over 83%. CONCLUSION: The SUP technique can reconstruct full 3D strain maps from tagged MR images through the cardiac cycle in a reasonable amount of time and user interaction compared to other 3D analysis methods.
No takes yet. Share an insight, caveat, or question.
Ambale‐Venkatesh et al. (2010) studied Left ventricular strain measurement (n=40). Strain from unwrapped phase (SUP) technique vs. Feature-based (FB) and HARP techniques was evaluated on Comparison of 3D strain maps and displacements (Correlation >83%). The strain from unwrapped phase (SUP) technique reconstructed full 3D strain maps from tagged MR images, demonstrating over 83% correlation with HARP techniques.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: