Anatomic Stereotactic Catheter Ablation on Three-Dimensional Magnetic Resonance Images in Real Time
Key result
Real-time display of an electromagnetic catheter positioning system on 3D MRI allowed accurate and precise RF ablation in a swine model, with an in vivo accuracy of 2.74+/-0.52 mm.
Why the study?
Does real-time display of catheter position on 3D MRI allow accurate and precise radiofrequency ablation guided by true anatomy in a preclinical model?
Population
In vitro phantom model and in vivo swine model
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Supports preclinical feasibility of fluoroscopy-free MRI-guided ablation; leaves open human translation and validation.
Structured PICO
Does real-time display of catheter position on 3D MRI allow accurate and precise radiofrequency ablation guided by true anatomy in a preclinical model?
P
Population
In vitro phantom model and in vivo swine model (n=7 for catheterization, n=8 for right atrial ablations, n=6 for ventricular ablations)
I
Intervention
Real-time display of catheter position on 3D MRI using an electromagnetic catheter positioning system superimposed with fiducial markers
O
Outcome
In vitro and in vivo accuracy and precision of catheter navigation, and reproducibility of radiofrequency ablation lesionssurrogate
Real-time display of catheter position on 3D MRI allows accurate and precise radiofrequency ablation in a swine model, demonstrating feasibility for anatomically based ablation procedures without fluoroscopy.
Cite This Study
Dickfeld et al. (2003) studied Radiofrequency ablation targets (atrial fibrillation, atrial flutter, ventricular tachycardia) (n=21). Electromagnetic catheter positioning system superimposed on 3D MR images was evaluated on In vitro and in vivo accuracy and precision during catheter navigation. Real-time display of an electromagnetic catheter positioning system on 3D MRI allowed accurate and precise RF ablation in a swine model, with an in vivo accuracy of 2.74+/-0.52 mm.