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Defective ion-channel proteins are responsible for various pathophysiological conditions, including cystic fibrosis, long-QT syndrome, and heritable hypertension, making them potential drug targets.
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Ion channels are fundamental to electrical signaling in the heart and other organs, and their defects are implicated in diseases such as long-QT syndrome.
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Ackerman et al. (1997) conducted a review in Ion channel diseases. Defective ion-channel proteins are responsible for various pathophysiological conditions, including cystic fibrosis, long-QT syndrome, and heritable hypertension, making them potential drug targets.
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