Key result
The PHARMFIT program provides a tool for nonlinear fitting of pharmacological and chronobiological data, including dose-response curves, pharmacokinetics, and cosine analysis of rhythms.
Population
Rats (telemetric heart rate data)
Design
Other
Authors
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May aid chronobiological data analysis; leaves open validation and adoption in clinical research.
PHARMFIT is a nonlinear fitting program designed for pharmacological and chronobiological data analysis.
Mattes et al. (1991) studied this question. PHARMFIT program was evaluated. The PHARMFIT program provides a tool for nonlinear fitting of pharmacological and chronobiological data, including dose-response curves, pharmacokinetics, and cosine analysis of rhythms.
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