Key result
Expanded reperfusion indications broaden stroke patient eligibility for disability-sparing thrombolysis and thrombectomy.
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This review highlights recent developments and expanded indications for acute reperfusion therapies in ischemic stroke, enabling broader patient access to disability-sparing treatments.
PURPOSE OF REVIEW: Advances in intravenous thrombolysis and endovascular thrombectomy have significantly reduced disability and improved outcomes associated with acute ischemic stroke. RECENT FINDINGS: An expansion of indications for reperfusion therapies in select groups of patients to permit treatment in an extended time window, with large ischemic core, and with simplified imaging protocols have enabled a broader group of patients access to disability-sparing therapy. Cerebroprotection has had renewed development in the era of acute reperfusion. SUMMARY: In this review, we highlight recent developments in stroke reperfusion research and related questions that are under study or remain unanswered.
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Nguyen et al. (2024) conducted a review in acute ischemic stroke. acute reperfusion therapies (intravenous thrombolysis and endovascular thrombectomy) was evaluated. Recent developments in stroke reperfusion research have expanded indications for intravenous thrombolysis and endovascular thrombectomy, enabling broader patient access to disability-sparing therapy.
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