Cryptocurrencies, such as Bitcoin and 250 similar alt-coins, embody at their core a blockchain protocol --- a mechanism for a distributed network of computational nodes to periodically agree on a set of new transactions. Designing a secure blockchain protocol relies on an open challenge in security, that of designing a highly-scalable agreement protocol open to manipulation by byzantine or arbitrarily malicious nodes. Bitcoin's blockchain agreement protocol exhibits security, but does not scale: it processes 3--7 transactions per second at present, irrespective of the available computation capacity at hand.
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Luu et al. (2016) studied this question.
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