Key result
ED patients with TIA or minor stroke face ~20% three-month stroke risk, peaking in week one.
Why the study?
The incidence of stroke after TIA is high in the first 90 days, but very few studies in India have assessed stroke risk and associated risk factors after TIA or minor ischemic stroke.
Observational (n=71)
No
Nearly 20% of patients presenting with TIA or minor ischemic stroke developed a stroke within 3 months, highlighting the need for aggressive early management.
High early stroke risk after TIA or minor stroke warrants close monitoring; leaves open optimal prevention strategies.
Background: The incidence of stroke after transient ischemic attack (TIA) has been observed to be high in the first 90 days. There are very few studies conducted in India to assess the risk of stroke in patients presenting with TIA. Hence, the primary aim of our study is to assess the risk of stroke in patients presenting to the emergency department (ED) with TIA or minor ischemic stroke (MIS) and the various risk factors associated with it. Materials and Methods: This was a prospective observational study done on consecutive patients who presented to our ED with neurovascular deficits suggestive of TIA or MIS within 16 h. Results: During the study period, a total of 71 patients were recruited. The mean age of the study group was 58.07 (standard deviation: 13.15) years. There was a male predominance of 70.4%. The incidence of TIA during the study period was 56 (78.9%) and that of MIS was 6 (8.5%) in our ED. Based on the magnetic resonance imaging stroke protocol finding, it was observed that among the TIA patients, about half of them had an infarct and 8.45% had a minor stroke with acute infarct. Overall, we observed that 19.7% of the recruited patients with TIA or MIS developed stroke within 3 months and majority of the clinical deterioration were in the 1st week post index event. Conclusion: TIA and MIS should be considered as a major ischemic event and should be treated aggressively with effective collaboration of various departments. Early diagnosis and proper treatment will help prevent further grave neurological deterioration.
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Lohanathan et al. (2020) conducted an observational in Transient ischemic attack (TIA) or minor ischemic stroke (MIS) (n=71). Observation was evaluated on Risk of stroke within 3 months. Among patients presenting to the emergency department with TIA or minor ischemic stroke, 19.7% developed a stroke within 3 months, with the majority of clinical deterioration occurring in the first week.
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