September 1, 1976American Journal of Psychiatry
Neuropsychological and EEG disturbances in polydrug users
Key result
Polydrug users exhibited significant cerebral dysfunction, with 43% showing EEG abnormalities and 45% having neuropsychological impairment at 3 weeks, and 27% remaining impaired at 5 months.
Study Design
Type
Cohort (n=66)
Structured PICO
P
Population
66 polydrug users admitted to a polydrug study unit
O
Outcome
EEG abnormalities and neuropsychological impairmentsurrogate
Polydrug users experience significant EEG and neuropsychological impairments that can persist beyond 5 months of reduced use or abstinence.
Authors
Discussion
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Implication
Persistent impairments may warrant extended neurocognitive monitoring in polydrug users; leaves open causality and recovery in prospective cohorts.
Cite This Study
Grant et al. (1976) conducted a cohort in Polydrug use (n=66). Reduced use or abstinence was evaluated on Neuropsychological impairment at 3 weeks. Polydrug users exhibited significant cerebral dysfunction, with 43% showing EEG abnormalities and 45% having neuropsychological impairment at 3 weeks, and 27% remaining impaired at 5 months.