Why the study?
Fluorographic myocardial staining during VOM-EI could predict procedural alcoholization outcomes, but its role is routinely assessed qualitatively rather than quantitatively.
Does a higher myocardial staining index during vein of Marshall ethanol infusion predict mitral isthmus block achievement in patients with persistent atrial fibrillation?
Population
42 patients with persistent AF and identifiable VOM undergoing catheter ablation
Comparison
Quantitative assessment of myocardial staining via a proposed index
Design
Single-center retrospective study
Key result
A higher myocardial staining index during vein of Marshall ethanol infusion was significantly associated with the achievement of mitral isthmus block (OR 1.24).
Authors
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MSI may aid mitral isthmus block prediction during VOM ethanol infusion; hypothesis-generating and requires prospective validation.
Observational (n=42)
No
Does a higher myocardial staining index during vein of Marshall ethanol infusion predict mitral isthmus block achievement in patients with persistent atrial fibrillation?
Effect estimate: OR 1.24 (95% CI 1.03-1.48)
p-value: p=0.022
A proposed quantitative index of myocardial staining during vein of Marshall ethanol infusion predicts successful mitral isthmus block and reduces required ablation time in patients with persistent atrial fibrillation.
Landra et al. (2024) conducted an observational in Persistent atrial fibrillation (PeAF) (n=42). Vein of Marshall ethanol infusion (VOM-EI) with myocardial staining index (MSI) assessment was evaluated on Occurrence of mitral isthmus (MI) block (OR 1.24, 95% CI 1.03-1.48, p=0.022). A higher myocardial staining index during vein of Marshall ethanol infusion was significantly associated with the achievement of mitral isthmus block (OR 1.24).