Key result
Second-generation cryoballoon ablation linked to ~32% shorter procedures versus radiofrequency in AF with common inferior PVs.
Why the study?
Procedural outcomes comparing cryoballoon ablation and radiofrequency ablation in AF patients with a common ostium of inferior pulmonary veins, as well as the anatomical effects on cryoballoon performance, were unknown.
Does second-generation cryoballoon ablation improve procedural outcomes and atrial arrhythmias-free survival compared to radiofrequency ablation in atrial fibrillation patients with the common ostium of inferior pulmonary veins?
Observational (n=18)
No
Does second-generation cryoballoon ablation improve procedural outcomes and atrial arrhythmias-free survival compared to radiofrequency ablation in atrial fibrillation patients with the common ostium of inferior pulmonary veins?
Answers are grounded in this paper and cite their sources.
Second-generation cryoballoon ablation is a feasible and safe alternative to radiofrequency ablation for atrial fibrillation patients with the common ostium of inferior pulmonary veins, offering shorter procedural times but requiring more fluoroscopy.
Aims: To compare the procedural outcomes of cryoballoon ablation (CBA) and radiofrequency ablation (RFA) in atrial fibrillation (AF) patients with the common ostium of inferior pulmonary veins (COIPV) and to explore the effect of COIPV on CBA performance through the assessment of anatomical factors. Methods: A total of 18 AF patients with COIPV were included. Pulmonary vein isolation (PVI) was performed with second-generation CBA or RFA. The anatomical characteristics of COIPV and procedural outcomes were collected. Results: The prevalence of COIPV was 0.82% in the enrolled population. PVI was achieved in all pulmonary veins (PVs) without any complications. The “tricircle” strategy was applied for RFA, and the segmental freeze strategy was performed for CBA. Compared with RFA, CBA had shorter procedural time (median: 53.0 vs. 78.0 min, p < 0.001) and longer fluoroscopy time (median: 13.5 vs. 6.0 min, p < 0.001). Higher ovality index of the ostium was seen in patients with ≥4 freezes in inferior PVs [IPVs; 0.95 (0.78–1.05) vs. 0.49 (0.21–0.83), p = 0.047]. During a median of 23.5 months of follow-up, the atrial arrhythmias-free survival after the procedure was comparable between CBA and RFA ( p = 0.729). Conclusion: The second-generation CBA is an efficient and safe alternative for RFA in AF patients with COIPV. Anatomical characteristics of COIPV bring the challenge to the procedure performance of RFA and CBA.
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Li et al. (2022) conducted an observational in Atrial fibrillation with common ostium of inferior pulmonary veins (n=18). Second-generation cryoballoon ablation vs. Radiofrequency ablation was evaluated on Procedure time (minutes) (p=<0.001). Second-generation cryoballoon ablation significantly reduced procedure time compared to radiofrequency ablation (median 53.0 vs 78.0 minutes) in atrial fibrillation patients with a common ostium of inferior pulmonary veins.
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