Key result
Reperfusion time >6 hours predicts ~14-fold higher no-reflow risk during primary angioplasty for AMI.
Population
181 consecutive patients with acute myocardial infarction who underwent Primary PCI, mean age 59.19±10.25…
Design
Case-control
Authors
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Longer reperfusion delays may raise no-reflow risk in primary PCI; leaves open whether earlier presentation improves outcomes in prospective studies.
Case-Control (n=181)
No
Effect estimate: OR 13.844 (95% CI 3.214-59.636)
p-value: p=<0.001
Longer reperfusion time, older age, long target lesions, and low initial TIMI flow are strong independent predictors of no-reflow during primary PCI for acute myocardial infarction.
Padmajan et al. (2017) conducted a case-control in Acute myocardial infarction (n=181). Reperfusion time > 6 h vs. Reperfusion time ≤ 6 h was evaluated on Angiographic no-reflow phenomenon (OR 13.844, 95% CI 3.214-59.636, p=<0.001). Reperfusion time > 6 hours independently predicted no-reflow during primary angioplasty for acute myocardial infarction with an OR of 13.844, alongside age >60 years, long target lesions, and low initial TIMI flow.
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