Key result
Any T-wave abnormality on presenting ECG in potential ACS patients was associated with higher 30-day cardiovascular events compared to no abnormalities (10.8% vs 5.7%; RR 1.9; 95% CI 1.6-2.3).
Why the study?
Do T-wave abnormalities on the presenting ECG predict 30-day cardiovascular events in emergency department patients with potential acute coronary syndromes?
Population
5,582 emergency department patients presenting with potential acute coronary syndromes. Excluded: prior…
Comparison
Presence of T-wave abnormalities on presenting ECG vs Absence of T-wave abnormalities on presenting ECG
Design
Cohort
Follow-up
30 days
Authors
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T-wave abnormalities may aid ED risk stratification in potential ACS; leaves open whether they improve outcomes beyond troponin in prospective studies.
Cohort (n=5,582)
Do T-wave abnormalities on the presenting ECG predict 30-day cardiovascular events in emergency department patients with potential acute coronary syndromes?
Effect estimate: RR 1.9 (95% CI 1.6 to 2.3)
Absolute Event Rate: 10.8% vs 5.7%
p-value: p=0.0001
In emergency department patients with potential ACS, T-wave abnormalities on the presenting ECG are associated with a significantly higher risk of 30-day cardiovascular events, independent of initial troponin levels.
Lin et al. (2008) conducted a cohort in potential acute coronary syndromes (ACSs) (n=5,582). Any T-wave abnormality vs. No T-wave abnormalities was evaluated on Composite of death, acute myocardial infarction, revascularization, coronary stenosis greater than 50%, or a stress test with reversible ischemia (RR 1.9, 95% CI 1.6 to 2.3, p=0.0001). Any T-wave abnormality on presenting ECG in potential ACS patients was associated with higher 30-day cardiovascular events compared to no abnormalities (10.8% vs 5.7%; RR 1.9; 95% CI 1.6-2.3).
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