Key result
SCORE2 low-risk model requires no recalibration to stratify cardiovascular risk in healthy Belgian adults.
Why the study?
Primary prevention of cardiovascular disease is poorly implemented, and a new model (SCORE 2) was developed to estimate total cardiovascular risk with advantages over the previously recommended SCORE-Belgium model.
Is the SCORE 2 low-risk model appropriate for estimating total cardiovascular risk in the apparently healthy adult population in Belgium without recalibration?
Is the SCORE 2 low-risk model appropriate for estimating total cardiovascular risk in the apparently healthy adult population in Belgium without recalibration?
The SCORE 2 low-risk model is recommended for primary cardiovascular prevention in Belgium, providing an easy-to-use tool for risk stratification without the need for local recalibration.
Supports SCORE2 low-risk model for Belgian adults without recalibration; leaves open prospective validation in local cohorts.
SCORE 2: a new model to estimate total cardiovascular risk Primary prevention of cardiovascular disease (CVD) is needed, but poorly implemented. The choice of the most optimal preventive strategy depends on the total cardiovascular (CV) risk of a given person. Models have been developed to estimate the total CV risk. Until recently, the SCORE model calibrated for Belgium (SCORE-Belgium) was recommended for that purpose. A new model has now been developed and validated (SCORE 2) with many advantages. Four systems have been advocated and the SCORE 2 low-risk system has been recommended for Belgium. It is easy to use and it allows the stratification of the apparently healthy adult population into subgroups with a low to moderate, high and very high total CV risk. Preventive strategies can then be adapted accordingly. A recalibration of this SCORE 2 low-risk model for Belgium seems unnecessary. The international model, however, seems to slightly underestimate the total CV risk in the population, which is in accordance with the position of Belgium as one of the countries with the highest CV mortality rates within the 10 countries that are considered being at low CV risk. This marginal difference does not justify a recalibration of the international model.
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Backer et al. (2022) conducted a review in Cardiovascular disease. SCORE 2 low-risk model was evaluated. The SCORE 2 low-risk model is recommended for stratifying total cardiovascular risk in apparently healthy adults in Belgium, with no recalibration deemed necessary despite slight risk underestimation.
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