What question did this study set out to answer?

To establish the most accurate diagnostic definition of hypopnea and assess how frequently patients exhibit the clinical syndrome of sleep apnea in the absence of recurrent complete apneas.

April 1, 1988American Review of Respiratory Disease

The Sleep Hypopnea Syndrome

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Authors

GGG A GouldYale University KWK. WhyteAuckland City Hospital GRG B RhindCollaborative Group (United States)

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Implication

Observational study reveals significant nocturnal desaturations and arousals from recurrent hypopneas in symptomatic patients, indicating sleep apnea syndrome can occur without complete apneas.

Key Points

To establish the most accurate diagnostic definition of hypopnea and assess how frequently patients exhibit the clinical syndrome of sleep apnea in the absence of recurrent complete apneas.
Analyzed nocturnal breathing patterns, oxygen saturation, and sleep architecture in 50 consecutive patients referred with clinical features of sleep apnea syndrome and abnormal breathing.
Compared hypopnea diagnostic criteria based on thoracoabdominal movement versus airflow reduction, validating criteria against 33 healthy normal subjects.
A 50% reduction in thoracoabdominal movement lasting at least 10 seconds was the most accurate definition, yielding fewer than 11 hypopneas/h and fewer than 14 total events/h in all 33 normal subjects.
Among the 50 patients, 18 had fewer than 10 apneas/h but experienced 9 to 98 hypopneas/h, resulting in all 50 patients exceeding 16 apneas plus hypopneas/h.
Patients with recurrent hypopneas alone were clinically indistinguishable from those with recurrent apneas, exhibiting comparable rates of 4% oxygen desaturation (0 to 104/h) and sleep arousals (7 to 98/h).

Cite This Study

Gould et al. (1988) studied this question.

synapsesocial.com/papers/6a0f529057bfcc72645f9ef7 https://doi.org/10.1164/ajrccm/137.4.895

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Implication

Observational study reveals significant nocturnal desaturations and arousals from recurrent hypopneas in symptomatic patients, indicating sleep apnea syndrome can occur without complete apneas.

The Sleep Hypopnea Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

The Sleep Hypopnea Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider